AUGMENTIN CHEWABLE Dosage & Rx Info | Uses, Side Effects

Miscellaneous: Tooth discoloration brown, yellow, or gray staining has been reported. Hemic and Lymphatic Systems Anemia, including hemolytic anemia, thrombocytopenia, thrombocytopenic purpura, eosinophilia, leukopenia, and agranulocytosis have been reported during therapy with penicillins. Most reports occurred in pediatric patients. A high percentage of patients with mononucleosis who receive ampicillin develop an erythematous skin rash.

Appropriate fluid and electrolyte management, protein supplementation, antibacterial treatment of C. Skin Rash in Patients with Mononucleosis A high percentage of patients with mononucleosis who receive amoxicillin develop an erythematous skin rash. Thus, Augmentin should not be administered to patients with mononucleosis. Potential for Microbial Overgrowth The possibility of superinfections with fungal or bacterial pathogens should be considered during therapy.

Phenylketonurics Augmentin Chewable tablets and Augmentin Powder for Oral Solution contain aspartame which contains phenylalanine. Each mg chewable tablet of Augmentin contains 2. The other formulations of Augmentin do not contain phenylalanine. Adverse Reactions The following are discussed in more detail in other sections of the labeling: Anaphylactic reactions [see Warnings and Precautions 5. The overall incidence of adverse reactions, and in particular diarrhea, increased with the higher recommended dose.

A total of patients were enrolled, and only the suspension formulations were used in this trial. Because they are reported voluntarily from a population of unknown size, estimates of frequency cannot be made. These events have been chosen for inclusion due to a combination of their seriousness, frequency of reporting, or potential causal connection to Augmentin. Onset of pseudomembranous colitis symptoms may occur during or after antibiotic treatment.

It has been reported more commonly in the elderly, in males, or in patients on prolonged treatment. The hepatic dysfunction, which may be severe, is usually reversible. Deaths have been reported. These reactions are usually reversible on discontinuation of therapy and are believed to be hypersensitivity phenomena.

There have been reports of increased prothrombin time in patients receiving Augmentin and anticoagulant therapy concomitantly.

Miscellaneous: Tooth discoloration brown, yellow, or gray staining has been reported. Most reports occurred in pediatric patients. Discoloration was reduced or eliminated with brushing or dental cleaning in most cases. Drug Interactions Probenecid Probenecid decreases the renal tubular secretion of amoxicillin but does not delay renal excretion of clavulanic acid. Concurrent use with Augmentin may result in increased and prolonged blood concentrations of amoxicillin.

Coadministration of probenecid is not recommended. Oral Anticoagulants Abnormal prolongation of prothrombin time increased international normalized ratio [INR] has been reported in patients receiving amoxicillin and oral anticoagulants. Appropriate monitoring should be undertaken when anticoagulants are prescribed concurrently with Augmentin.

Adjustments in the dose of oral anticoagulants may be necessary to maintain the desired level of anticoagulation. Allopurinol The concurrent administration of allopurinol and amoxicillin increases the incidence of rashes in patients receiving both drugs as compared to patients receiving amoxicillin alone.

It is not known whether this potentiation of amoxicillin rashes is due to allopurinol or the hyperuricemia present in these patients. Since this effect may also occur with Augmentin, it is recommended that glucose tests based on enzymatic glucose oxidase reactions be used.

Following administration of amoxicillin to pregnant women, a transient decrease in plasma concentration of total conjugated estriol, estriol-glucuronide, conjugated estrone, and estradiol has been noted. Skipping doses or not completing the full course of therapy may: 1 decrease the effectiveness of the immediate treatment, and 2 increase the likelihood that bacteria will develop resistance and will not be treatable by AUGMENTIN or other antibacterial drugs in the future.

Contact your physician or pharmacist. Drug Interactions Probenecid decreases the renal tubular secretion of amoxicillin. Coadministration of probenecid cannot be recommended. Abnormal prolongation of prothrombin time increased international normalized ratio [INR] has been reported rarely in patients receiving amoxicillin and oral anticoagulants. Appropriate monitoring should be undertaken when anticoagulants are prescribed concurrently.

Adjustments in the dose of oral anticoagulants may be necessary to maintain the desired level of anticoagulation. The concurrent administration of allopurinol and ampicillin increases substantially the incidence of rashes in patients receiving both drugs as compared to patients receiving ampicillin alone.

It is not known whether this potentiation of ampicillin rashes is due to allopurinol or the hyperuricemia present in these patients. Following administration of ampicillin to pregnant women, a transient decrease in plasma concentration of total conjugated estriol, estriol-glucuronide, conjugated estrone, and estradiol has been noted. Carcinogenesis, Mutagenesis, Impairment of Fertility Long-term studies in animals have not been performed to evaluate carcinogenic potential. Mutagenesis The mutagenic potential of AUGMENTIN was investigated in vitro with an Ames test, a human lymphocyte cytogenetic assay, a yeast test and a mouse lymphoma forward mutation assay, and in vivo with mouse micronucleus tests and a dominant lethal test.

All were negative apart from the in vitro mouse lymphoma assay where weak activity was found at very high, cytotoxic concentrations.

There are, however, no adequate and well-controlled studies in pregnant women. Because animal reproduction studies are not always predictive of human response, this drug should be used during pregnancy only if clearly needed. Labor and Delivery Oral ampicillin-class antibiotics are generally poorly absorbed during labor. Studies in guinea pigs have shown that intravenous administration of ampicillin decreased the uterine tone, frequency of contractions, height of contractions, and duration of contractions.

However, it is not known whether the use of AUGMENTIN in humans during labor or delivery has immediate or delayed adverse effects on the fetus, prolongs the duration of labor, or increases the likelihood that forceps delivery or other obstetrical intervention or resuscitation of the newborn will be necessary. In a single study in women with premature rupture of fetal membranes, it was reported that prophylactic treatment with AUGMENTIN may be associated with an increased risk of necrotizing enterocolitis in neonates.

Pediatric Use Because of incompletely developed renal function in neonates and young infants, the elimination of amoxicillin may be delayed. The overall incidence of side effects, and in particular diarrhea, increased with the higher recommended dose.

Other less frequently reported reactions include: Abdominal discomfort, flatulence, and headache. A total of patients were enrolled, and only the suspension formulations were used in this trial. Onset of pseudomembranous colitis symptoms may occur during or after antibiotic treatment.

These reactions may be controlled with antihistamines and, if necessary, systemic corticosteroids. Whenever such reactions occur, the drug should be discontinued, unless the opinion of the physician dictates otherwise. Serious and occasional fatal hypersensitivity anaphylactic reactions can occur with oral penicillin.

It has been reported more commonly in the elderly, in males, or in patients on prolonged treatment. The histologic findings on liver biopsy have consisted of predominantly cholestatic, hepatocellular, or mixed cholestatic-hepatocellular changes.

The hepatic dysfunction, which may be severe, is usually reversible. Renal Interstitial nephritis and hematuria have been reported rarely. Hemic and Lymphatic Systems Anemia, including hemolytic anemia, thrombocytopenia, thrombocytopenic purpura, eosinophilia, leukopenia, and agranulocytosis have been reported during therapy with penicillins.

These reactions are usually reversible on discontinuation of therapy and are believed to be hypersensitivity phenomena.

Central Nervous System Agitation, anxiety, behavioral changes, confusion, convulsions, dizziness, insomnia, and reversible hyperactivity have been reported rarely. Miscellaneous Tooth discoloration brown, yellow, or gray staining has been rarely reported.

Most reports occurred in pediatric patients. Discoloration was reduced or eliminated with brushing or dental cleaning in most cases.

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Ask your doctor about using a non-hormone method of birth control such as a condom, diaphragm, 500 to prevent pregnancy while taking amoxicillin and clavulanate chewable. Follow all directions on your prescription label and read 125 medication guides or instruction sheets. Warnings You should not use Augmentin augmentin you have severe kidney disease, if you have had liver problems or jaundice while taking amoxicillin and clavulanate potassium, or if you are allergic to any penicillin or cephalosporin antibiotic, Before 500 this supplied You Blog not use Augmentin if you are allergic to amoxicillin and clavulanate or if: you have severe kidney disease or if you how on dialysis ; augmentin have had liver problems 125 jaundice while taking amoxicillin and clavulanate potassium; or augmentin are allergic to any penicillin or cephalosporin antibiotic, such as Amoxil, Ceftin, Cefzil, Moxatag, Omnicef, and others.

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Take exactly as directed by your doctor and complete the course as prescribed to reduce the risk of bacterial resistance developing.

Augmentin side effects Get emergency chewable help if you have signs of an allergic reaction to Augmentin hivesdifficult breathing, swelling in your face page throat or a severe skin reaction fever, sore throatburning eyes, skin pain, red or purple skin rash with blistering and peeling.

Amoxicillin and clavulanate potassium can pass interaction effect ocp bactrim breast milk and may harm a nursing baby.

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Tell your doctor if you have phenylketonuria PKU. Tell your doctor if you are pregnant or breastfeeding. Ask your doctor about using a non-hormonal birth control condom, diaphragm , cervical cap, or contraceptive sponge to prevent pregnancy. Do not give this medicine to a child without medical advice. How should I take Augmentin? Take Augmentin exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets.

Augmentin may work best if you take it at the start of a meal. Take the medicine every 12 hours. Do not crush or chew the extended-release tablet. Swallow the pill whole, or break the pill in half and take both halves one at a time. Tell your doctor if you have trouble swallowing a whole or half pill. Shake the oral suspension liquid before you measure a dose.

Use the dosing syringe provided, or use a medicine dose-measuring device not a kitchen spoon. This medicine can affect the results of certain medical tests. Tell any doctor who treats you that you are using Augmentin. Use this medicine for the full prescribed length of time, even if your symptoms quickly improve.

Skipping doses can increase your risk of infection that is resistant to medication. Augmentin will not treat a viral infection such as the flu or a common cold. Store the tablets at room temperature away from moisture and heat. Store the liquid in the refrigerator. Throw away any unused liquid after 10 days. Detailed Augmentin dosage information What happens if I miss a dose?

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Its use may be limited by resistance and side effects such as diarrhea and yeast overgrowth. Tips Take at the start of a light meal to improve the absorption of clavulanate potassium and to minimize the potential for gastrointestinal intolerance. Take exactly as directed by your doctor and complete the course as prescribed to reduce the risk of bacterial resistance developing.

Do not take if you are allergic to penicillin or any other penicillin-like antibiotic such as ampicillin, dicloxacillin, oxacillin, or others. Call for emergency help if you experience any allergic-type reactions including a rash; a swelling of the face, lips, or throat; difficulty breathing; or a tightness in the chest. Augmentin may encourage the overgrowth of yeasts, such as Candida. This may be seen as oral or vaginal thrush. See your doctor if you suspect you have developed thrush as a result of Augmentin use.

See your doctor if you develop prolonged or significant diarrhea while taking Augmentin or within several months of finishing the course. May cause tooth discoloration brown, yellow, or gray staining ; the risk is higher in pediatric patients.

Brushing or professional dental cleaning reduces or eliminates discoloration. Phenylketonurics should avoid Augmentin chewable tablets and Augmentin powder for oral solution which both contain aspartame this contains phenylalanine. Response and Effectiveness Peak concentrations are usually seen within 1. Some bacteria are inherently resistant to Augmentin whereas others can acquire resistance.